Caren Blumberg is seriously ill and urgently needs a new kidney. Her husband Sebi is not a suitable donor - due to a lack of suitable medical values. The situation is similar for a second couple, patient Jan Kempe and his wife Birthe. The common kidney specialist, Dr. Vollhard, suggests that the four of them donate their organs crosswise. However, in order to do so, the participants must prove to an ethics committee that the organ donation is done of their own free will, motivated by a special personal bond. In other words, the quartet has to prove that they are close friends. But the four quickly realise: basically, they don't like each other very much. Is their attempt at friendship - and thus their mutual organ donation - doomed to failure?